Summary
This is the summary of UniProt entry RPOB_VIBCH (Q9KV30).
| Description: | DNA-directed RNA polymerase subunit beta EC=2.7.7.6 |
| Source organism: |
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
(NCBI taxonomy ID
243277)
View Pfam proteome data. |
| Length: | 1341 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | RNA_pol_Rpb2_1 | 26 | 509 |
| Pfam A | RNA_pol_Rpb2_2 | 151 | 278 |
| Pfam A | RNA_pol_Rpb2_2 | 315 | 454 |
| disorder | n/a | 411 | 413 |
| Pfam A | RNA_pol_Rpb2_3 | 513 | 582 |
| disorder | n/a | 517 | 518 |
| disorder | n/a | 525 | 526 |
| Pfam A | RNA_pol_Rpb2_45 | 591 | 656 |
| disorder | n/a | 634 | 638 |
| disorder | n/a | 640 | 641 |
| disorder | n/a | 645 | 649 |
| disorder | n/a | 681 | 685 |
| disorder | n/a | 691 | 692 |
| disorder | n/a | 694 | 696 |
| Pfam A | RNA_pol_Rpb2_6 | 715 | 1263 |
| disorder | n/a | 764 | 765 |
| disorder | n/a | 767 | 770 |
| disorder | n/a | 776 | 779 |
| disorder | n/a | 781 | 783 |
| disorder | n/a | 888 | 889 |
| coiled_coil | n/a | 936 | 963 |
| coiled_coil | n/a | 997 | 1031 |
| low_complexity | n/a | 998 | 1017 |
| disorder | n/a | 1070 | 1075 |
| disorder | n/a | 1078 | 1084 |
| disorder | n/a | 1089 | 1091 |
| disorder | n/a | 1162 | 1163 |
| Pfam A | RNA_pol_Rpb2_7 | 1265 | 1341 |
| disorder | n/a | 1308 | 1310 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q9KV30. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MVYSYTEKKR IRKDFGTRPQ VLDIPYLLSI QLDSFEKFIE QDPEGQYGLE
50 51
AAFRSVFPIQ SYNGNSELQY VSYRLGEPVF DVKECQIRGV TYSKPLRVKL
100 101
RLVIFDKDAP AGTVKDIKEQ EVYMGEIPLM TENGTFVING TERVIVSQLH
150 151
RSPGVFFDSD KGKTHSSGKV LYNARIIPYR GSWLDFEFDP KDNLYVRIDR
200 201
RRKLPASIIL RALGKTSAEI LDIFFEKVNF EVKDQTLMME LVPERLRGET
250 251
ATFDIEADGK VYVEKGRRVT ARHIRQLEKD GVNFIEVPVE YIVGKVSAKD
300 301
YVNEATGELI ITANQEISLE ALANLSQAGY KKLEVLFTND LDHGPFMSET
350 351
LRVDSTTDRI SALVEIYRMM RPGEPPTKEA AESLFESLFF SAERYDLSTV
400 401
GRMKFNSSIG REDAEEQGTL DEVDIIEVMK KLISIRNGKG EVDDIDHLGN
450 451
RRIRSVGEMA ENQFRVGLVR VERAVKERLS LGDLDNVMPQ DLINAKPISA
500 501
AVKEFFGSSQ LSQFMDQNNP LSEVTHKRRI SALGPGGLTR ERAGFEVRDV
550 551
HVTHYGRLCP IETPEGPNIG LINSLSAFAR CNEYGFLETP YRRVVNGVVT
600 601
DEVDYLSAIE EGQFVIAQAN AKLTEEGGFA DELVTARQKG ESGLHPREHV
650 651
DYMDVATNQV VSIAASLIPF LEHDDANRAL MGANMQRQAV PTLRSEKPLV
700 701
GTGIERNVAV DSGVTAVAKR GGVIQSVDAS RIVVKVNEEE LIPGEAGIDI
750 751
YNLTKYTRSN QNTCINQRPC VMPGEPVARG DVLADGPSTD LGELALGQNM
800 801
RIAFMPWNGY NFEDSILVSE RVVQDDRFTT IHIQELSCVA RDTKLGAEEI
850 851
TADIPNVGEA ALSKLDESGI VYIGAEVKGG DILVGKVTPK GETQLTPEEK
900 901
LLRAIFGEKA SDVKDTSLRV PNSVAGTVID VQVFTRDGVE KDKRALEIEQ
950 951
MQLKEAKKDL TEEFQILEGG LLARVRSVLL AGGYTEAKLG SIERKKWLEQ
1000 1001
TLENEELQNQ LEQLAEQYDE LKADFDKKFE AKRRKITQGD DLAPGVLKIV
1050 1051
KVYLAVKRRI QPGDKMAGRH GNKGVISKIN PVEDMPYDEN GQPVDIVLNP
1100 1101
LGVPSRMNIG QILEVHLGLA AKGIGDKINQ MIKEQQELAK LREFLQKVYD
1150 1151
LGDTRQRVDI SELSDEDVRT LAHNLRAGLP VATPVFDGAP ESSIKAMLEL
1200 1201
ADLPASGQLT LFDGRTGDAF ERPVTVGYMY MLKLNHLVDD KMHARSTGSY
1250 1251
SLVTQQPLGG KAQFGGQRFG EMEVWALEAY GAAYTLQEML TVKSDDVNGR
1300 1301
TKMYKNIVDG NHAMEPGMPE SFNVLLKEIR SLGINIELED E
1341
Show the unformatted sequence. |
| Checksums: |
CRC64:9C6C824A923295A9
MD5:3a67fa44d6f91b7fb8855108e82138bc
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| RNA_pol_Rpb2_1 | 228 - 327 | 3E7H | B | 1 - 100 | Jmol AstexViewer SPICE |
| 228 - 328 | 3E7H | A | 1 - 101 | Jmol AstexViewer SPICE | |
| RNA_pol_Rpb2_2 | 228 - 278 | 3E7H | A | 1 - 51 | Jmol AstexViewer SPICE |
| B | 1 - 51 | Jmol AstexViewer SPICE | |||
| 315 - 327 | 3E7H | B | 88 - 100 | Jmol AstexViewer SPICE | |
| 315 - 328 | 3E7H | A | 88 - 101 | Jmol AstexViewer SPICE |