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31  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DPOLL_HUMAN (Q9UGP5)

Summary

This is the summary of UniProt entry DPOLL_HUMAN (Q9UGP5).

Description: DNA polymerase lambda EC=2.7.7.7 EC=4.2.99.-
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 575 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 27 28
low_complexity n/a 32 39
disorder n/a 77 79
low_complexity n/a 93 109
disorder n/a 143 211
low_complexity n/a 168 179
disorder n/a 220 228
disorder n/a 238 242
disorder n/a 250 254
Pfam A HHH_8 253 318
Pfam A DNA_pol_lambd_f 335 385
Pfam A DNA_pol_B_palm 386 496
disorder n/a 394 398
disorder n/a 473 475
low_complexity n/a 478 489
Pfam A DNA_pol_B_thumb 502 575
disorder n/a 546 548

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UGP5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDPRGILKAF PKRQKIHADA SSKVLAKIPR REEGEEAEEW LSSLRAHVVR
50
51
TGIGRARAEL FEKQIVQHGG QLCPAQGPGV THIVVDEGMD YERALRLLRL
100
101
PQLPPGAQLV KSAWLSLCLQ ERRLVDVAGF SIFIPSRYLD HPQPSKAEQD
150
151
ASIPPGTHEA LLQTALSPPP PPTRPVSPPQ KAKEAPNTQA QPISDDEASD
200
201
GEETQVSAAD LEALISGHYP TSLEGDCEPS PAPAVLDKWV CAQPSSQKAT
250
251
NHNLHITEKL EVLAKAYSVQ GDKWRALGYA KAINALKSFH KPVTSYQEAC
300
301
SIPGIGKRMA EKIIEILESG HLRKLDHISE SVPVLELFSN IWGAGTKTAQ
350
351
MWYQQGFRSL EDIRSQASLT TQQAIGLKHY SDFLERMPRE EATEIEQTVQ
400
401
KAAQAFNSGL LCVACGSYRR GKATCGDVDV LITHPDGRSH RGIFSRLLDS
450
451
LRQEGFLTDD LVSQEENGQQ QKYLGVCRLP GPGRRHRRLD IIVVPYSEFA
500
501
CALLYFTGSA HFNRSMRALA KTKGMSLSEH ALSTAVVRNT HGCKVGPGRV
550
551
LPTPTEKDVF RLLGLPYREP AERDW                           
575
 

Show the unformatted sequence.

Checksums:
CRC64:FD9196A1C94923C4
MD5:c120becf7108838ff7988a98dd572fe1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
DNA_pol_B_palm 386 - 496 1RZT A 386 - 496 Jmol AstexViewer SPICE
E 386 - 496 Jmol AstexViewer SPICE
I 386 - 496 Jmol AstexViewer SPICE
M 386 - 496 Jmol AstexViewer SPICE
1XSL A 386 - 496 Jmol AstexViewer SPICE
E 386 - 496 Jmol AstexViewer SPICE
I 386 - 496 Jmol AstexViewer SPICE
M 386 - 496 Jmol AstexViewer SPICE
1XSN A 386 - 496 Jmol AstexViewer SPICE
1XSP A 386 - 496 Jmol AstexViewer SPICE
2BCQ A 386 - 496 Jmol AstexViewer SPICE
2BCR A 386 - 496 Jmol AstexViewer SPICE
2BCS A 386 - 496 Jmol AstexViewer SPICE
2BCU A 386 - 496 Jmol AstexViewer SPICE
2BCV A 386 - 496 Jmol AstexViewer SPICE
2GWS A 386 - 496 Jmol AstexViewer SPICE
E 386 - 496 Jmol AstexViewer SPICE
I 386 - 496 Jmol AstexViewer SPICE
M 386 - 496 Jmol AstexViewer SPICE
2PFN A 386 - 496 Jmol AstexViewer SPICE
2PFO A 386 - 496 Jmol AstexViewer SPICE
2PFP A 386 - 496 Jmol AstexViewer SPICE
2PFQ A 386 - 496 Jmol AstexViewer SPICE
3C5F A 386 - 496 Jmol AstexViewer SPICE
B 386 - 496 Jmol AstexViewer SPICE
3C5G A 386 - 496 Jmol AstexViewer SPICE
B 386 - 496 Jmol AstexViewer SPICE
3HW8 A 386 - 496 Jmol AstexViewer SPICE
3HWT A 386 - 496 Jmol AstexViewer SPICE
3HX0 A 386 - 496 Jmol AstexViewer SPICE
F 386 - 496 Jmol AstexViewer SPICE
K 386 - 496 Jmol AstexViewer SPICE
P 386 - 496 Jmol AstexViewer SPICE
3MDA A 386 - 496 Jmol AstexViewer SPICE
3MDC A 386 - 496 Jmol AstexViewer SPICE
3MGH A 386 - 496 Jmol AstexViewer SPICE
C 386 - 496 Jmol AstexViewer SPICE
3MGI A 386 - 496 Jmol AstexViewer SPICE
3PML A 386 - 496 Jmol AstexViewer SPICE
B 386 - 496 Jmol AstexViewer SPICE
3PMN A 386 - 496 Jmol AstexViewer SPICE
3PNC A 386 - 496 Jmol AstexViewer SPICE
3UPQ A 386 - 496 Jmol AstexViewer SPICE
3UQ0 A 386 - 496 Jmol AstexViewer SPICE
3UQ1 A 386 - 496 Jmol AstexViewer SPICE
3UQ2 A 386 - 496 Jmol AstexViewer SPICE
DNA_pol_B_thumb 502 - 575 1RZT A 502 - 575 Jmol AstexViewer SPICE
E 502 - 575 Jmol AstexViewer SPICE
I 502 - 575 Jmol AstexViewer SPICE
M 502 - 575 Jmol AstexViewer SPICE
1XSL A 502 - 575 Jmol AstexViewer SPICE
E 502 - 575 Jmol AstexViewer SPICE
I 502 - 575 Jmol AstexViewer SPICE
M 502 - 575 Jmol AstexViewer SPICE
1XSN A 502 - 575 Jmol AstexViewer SPICE
1XSP A 502 - 575 Jmol AstexViewer SPICE
2BCQ A 502 - 575 Jmol AstexViewer SPICE
2BCR A 502 - 575 Jmol AstexViewer SPICE
2BCS A 502 - 575 Jmol AstexViewer SPICE
2BCU A 502 - 575 Jmol AstexViewer SPICE
2BCV A 502 - 575 Jmol AstexViewer SPICE
2GWS A 502 - 575 Jmol AstexViewer SPICE
E 502 - 575 Jmol AstexViewer SPICE
I 502 - 575 Jmol AstexViewer SPICE
M 502 - 575 Jmol AstexViewer SPICE
2PFN A 502 - 575 Jmol AstexViewer SPICE
2PFO A 502 - 575 Jmol AstexViewer SPICE
2PFP A 502 - 575 Jmol AstexViewer SPICE
2PFQ A 502 - 575 Jmol AstexViewer SPICE
3C5F A 502 - 575 Jmol AstexViewer SPICE
B 502 - 575 Jmol AstexViewer SPICE
3C5G A 502 - 575 Jmol AstexViewer SPICE
B 502 - 575 Jmol AstexViewer SPICE
3HW8 A 502 - 575 Jmol AstexViewer SPICE
3HWT A 502 - 575 Jmol AstexViewer SPICE
3HX0 A 502 - 575 Jmol AstexViewer SPICE
F 502 - 575 Jmol AstexViewer SPICE
K 502 - 575 Jmol AstexViewer SPICE
P 502 - 575 Jmol AstexViewer SPICE
3MDA A 502 - 575 Jmol AstexViewer SPICE
3MDC A 502 - 575 Jmol AstexViewer SPICE
3MGH A 502 - 575 Jmol AstexViewer SPICE
C 502 - 575 Jmol AstexViewer SPICE
3MGI A 502 - 575 Jmol AstexViewer SPICE
3PML A 502 - 575 Jmol AstexViewer SPICE
B 502 - 575 Jmol AstexViewer SPICE
3PMN A 502 - 575 Jmol AstexViewer SPICE
3PNC A 502 - 575 Jmol AstexViewer SPICE
3UPQ A 502 - 575 Jmol AstexViewer SPICE
3UQ0 A 502 - 575 Jmol AstexViewer SPICE
3UQ1 A 502 - 575 Jmol AstexViewer SPICE
3UQ2 A 502 - 575 Jmol AstexViewer SPICE
DNA_pol_lambd_f 335 - 385 1RZT A 335 - 385 Jmol AstexViewer SPICE
E 335 - 385 Jmol AstexViewer SPICE
I 335 - 385 Jmol AstexViewer SPICE
M 335 - 385 Jmol AstexViewer SPICE
1XSL A 335 - 385 Jmol AstexViewer SPICE
E 335 - 385 Jmol AstexViewer SPICE
I 335 - 385 Jmol AstexViewer SPICE
M 335 - 385 Jmol AstexViewer SPICE
1XSN A 335 - 385 Jmol AstexViewer SPICE
1XSP A 335 - 385 Jmol AstexViewer SPICE
2BCQ A 335 - 385 Jmol AstexViewer SPICE
2BCR A 335 - 385 Jmol AstexViewer SPICE
2BCS A 335 - 385 Jmol AstexViewer SPICE
2BCU A 335 - 385 Jmol AstexViewer SPICE
2BCV A 335 - 385 Jmol AstexViewer SPICE
2GWS A 335 - 385 Jmol AstexViewer SPICE
E 335 - 385 Jmol AstexViewer SPICE
I 335 - 385 Jmol AstexViewer SPICE
M 335 - 385 Jmol AstexViewer SPICE
2PFN A 335 - 385 Jmol AstexViewer SPICE
2PFO A 335 - 385 Jmol AstexViewer SPICE
2PFP A 335 - 385 Jmol AstexViewer SPICE
2PFQ A 335 - 385 Jmol AstexViewer SPICE
3C5F A 335 - 385 Jmol AstexViewer SPICE
B 335 - 385 Jmol AstexViewer SPICE
3C5G A 335 - 385 Jmol AstexViewer SPICE
B 335 - 385 Jmol AstexViewer SPICE
3HW8 A 335 - 385 Jmol AstexViewer SPICE
3HWT A 335 - 385 Jmol AstexViewer SPICE
3HX0 A 335 - 385 Jmol AstexViewer SPICE
F 335 - 385 Jmol AstexViewer SPICE
K 335 - 385 Jmol AstexViewer SPICE
P 335 - 385 Jmol AstexViewer SPICE
3MDA A 335 - 385 Jmol AstexViewer SPICE
3MDC A 335 - 385 Jmol AstexViewer SPICE
3MGH A 335 - 385 Jmol AstexViewer SPICE
C 335 - 385 Jmol AstexViewer SPICE
3MGI A 335 - 385 Jmol AstexViewer SPICE
3PML A 335 - 385 Jmol AstexViewer SPICE
B 335 - 385 Jmol AstexViewer SPICE
3PMN A 335 - 385 Jmol AstexViewer SPICE
3PNC A 335 - 385 Jmol AstexViewer SPICE
3UPQ A 335 - 385 Jmol AstexViewer SPICE
3UQ0 A 335 - 385 Jmol AstexViewer SPICE
3UQ1 A 335 - 385 Jmol AstexViewer SPICE
3UQ2 A 335 - 385 Jmol AstexViewer SPICE
HHH_8 253 - 318 1NZP A 253 - 318 Jmol AstexViewer SPICE
1RZT A 253 - 318 Jmol AstexViewer SPICE
E 253 - 318 Jmol AstexViewer SPICE
I 253 - 318 Jmol AstexViewer SPICE
M 253 - 318 Jmol AstexViewer SPICE
1XSL A 253 - 318 Jmol AstexViewer SPICE
E 253 - 318 Jmol AstexViewer SPICE
I 253 - 318 Jmol AstexViewer SPICE
M 253 - 318 Jmol AstexViewer SPICE
1XSN A 253 - 318 Jmol AstexViewer SPICE
1XSP A 253 - 318 Jmol AstexViewer SPICE
2BCQ A 253 - 318 Jmol AstexViewer SPICE
2BCR A 253 - 318 Jmol AstexViewer SPICE
2BCS A 253 - 318 Jmol AstexViewer SPICE
2BCU A 253 - 318 Jmol AstexViewer SPICE
2BCV A 253 - 318 Jmol AstexViewer SPICE
2GWS A 253 - 318 Jmol AstexViewer SPICE
E 253 - 318 Jmol AstexViewer SPICE
I 253 - 318 Jmol AstexViewer SPICE
M 253 - 318 Jmol AstexViewer SPICE
2PFN A 253 - 318 Jmol AstexViewer SPICE
2PFO A 253 - 318 Jmol AstexViewer SPICE
2PFP A 253 - 318 Jmol AstexViewer SPICE
2PFQ A 253 - 318 Jmol AstexViewer SPICE
3C5F A 253 - 318 Jmol AstexViewer SPICE
B 253 - 318 Jmol AstexViewer SPICE
3C5G A 253 - 318 Jmol AstexViewer SPICE
B 253 - 318 Jmol AstexViewer SPICE
3HW8 A 253 - 318 Jmol AstexViewer SPICE
3HX0 A 253 - 318 Jmol AstexViewer SPICE
F 253 - 318 Jmol AstexViewer SPICE
K 253 - 318 Jmol AstexViewer SPICE
P 253 - 318 Jmol AstexViewer SPICE
3MDA A 253 - 318 Jmol AstexViewer SPICE
3MGH A 253 - 318 Jmol AstexViewer SPICE
C 253 - 318 Jmol AstexViewer SPICE
3MGI A 253 - 318 Jmol AstexViewer SPICE
3PML A 253 - 318 Jmol AstexViewer SPICE
B 253 - 318 Jmol AstexViewer SPICE
3PMN A 253 - 318 Jmol AstexViewer SPICE
3PNC A 253 - 318 Jmol AstexViewer SPICE
3UPQ A 253 - 318 Jmol AstexViewer SPICE
3UQ0 A 253 - 318 Jmol AstexViewer SPICE
3UQ1 A 253 - 318 Jmol AstexViewer SPICE
3UQ2 A 253 - 318 Jmol AstexViewer SPICE
254 - 318 3MDC A 254 - 318 Jmol AstexViewer SPICE
257 - 318 3HWT A 257 - 318 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.