Summary
This is the summary of UniProt entry TFR2_HUMAN (Q9UP52).
| Description: | Transferrin receptor protein 2 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 801 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 19 | 22 |
| disorder | n/a | 25 | 46 |
| low_complexity | n/a | 35 | 46 |
| disorder | n/a | 48 | 50 |
| disorder | n/a | 62 | 63 |
| disorder | n/a | 67 | 69 |
| transmembrane | n/a | 84 | 104 |
| disorder | n/a | 212 | 214 |
| Pfam A | PA | 236 | 333 |
| disorder | n/a | 258 | 259 |
| low_complexity | n/a | 262 | 277 |
| disorder | n/a | 303 | 313 |
| disorder | n/a | 315 | 319 |
| disorder | n/a | 334 | 339 |
| disorder | n/a | 346 | 347 |
| Pfam A | Peptidase_M28 | 423 | 610 |
| low_complexity | n/a | 617 | 630 |
| Pfam A | TFR_dimer | 668 | 793 |
| low_complexity | n/a | 741 | 751 |
| low_complexity | n/a | 753 | 766 |
| disorder | n/a | 759 | 760 |
| disorder | n/a | 762 | 764 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UP52. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MERLWGLFQR AQQLSPRSSQ TVYQRVEGPR KGHLEEEEED GEEGAETLAH
50 51
FCPMELRGPE PLGSRPRQPN LIPWAAAGRR AAPYLVLTAL LIFTGAFLLG
100 101
YVAFRGSCQA CGDSVLVVSE DVNYEPDLDF HQGRLYWSDL QAMFLQFLGE
150 151
GRLEDTIRQT SLRERVAGSA GMAALTQDIR AALSRQKLDH VWTDTHYVGL
200 201
QFPDPAHPNT LHWVDEAGKV GEQLPLEDPD VYCPYSAIGN VTGELVYAHY
250 251
GRPEDLQDLR ARGVDPVGRL LLVRVGVISF AQKVTNAQDF GAQGVLIYPE
300 301
PADFSQDPPK PSLSSQQAVY GHVHLGTGDP YTPGFPSFNQ TQFPPVASSG
350 351
LPSIPAQPIS ADIASRLLRK LKGPVAPQEW QGSLLGSPYH LGPGPRLRLV
400 401
VNNHRTSTPI NNIFGCIEGR SEPDHYVVIG AQRDAWGPGA AKSAVGTAIL
450 451
LELVRTFSSM VSNGFRPRRS LLFISWDGGD FGSVGSTEWL EGYLSVLHLK
500 501
AVVYVSLDNA VLGDDKFHAK TSPLLTSLIE SVLKQVDSPN HSGQTLYEQV
550 551
VFTNPSWDAE VIRPLPMDSS AYSFTAFVGV PAVEFSFMED DQAYPFLHTK
600 601
EDTYENLHKV LQGRLPAVAQ AVAQLAGQLL IRLSHDRLLP LDFGRYGDVV
650 651
LRHIGNLNEF SGDLKARGLT LQWVYSARGD YIRAAEKLRQ EIYSSEERDE
700 701
RLTRMYNVRI MRVEFYFLSQ YVSPADSPFR HIFMGRGDHT LGALLDHLRL
750 751
LRSNSSGTPG ATSSTGFQES RFRRQLALLT WTLQGAANAL SGDVWNIDNN
800 801
F
801
Show the unformatted sequence. |
| Checksums: |
CRC64:D3D3082BA835413A
MD5:72e6c29371dcf4129f83a13edccd024d
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.