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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CAH14_MOUSE (Q9WVT6)

Summary

This is the summary of UniProt entry CAH14_MOUSE (Q9WVT6).

Description: Carbonic anhydrase 14 EC=4.2.1.1
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 337 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 15
Pfam A Carb_anhydrase 22 278
disorder n/a 24 28
disorder n/a 30 44
disorder n/a 67 77
disorder n/a 80 84
disorder n/a 119 127
disorder n/a 245 253
disorder n/a 255 257
disorder n/a 259 262
transmembrane n/a 290 312
low_complexity n/a 291 308

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9WVT6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLFFALLLKV TWILAADGGH HWTYEGPHGQ DHWPTSYPEC GGDAQSPINI
50
51
QTDSVIFDPD LPAVQPHGYD QLGTEPLDLH NNGHTVQLSL PPTLHLGGLP
100
101
RKYTAAQLHL HWGQRGSLEG SEHQINSEAT AAELHVVHYD SQSYSSLSEA
150
151
AQKPQGLAVL GILIEVGETE NPAYDHILSR LHEIRYKDQK TSVPPFSVRE
200
201
LFPQQLEQFF RYNGSLTTPP CYQSVLWTVF NRRAQISMGQ LEKLQETLSS
250
251
TEEDPSEPLV QNYRVPQPLN QRTIFASFIQ AGPLYTTGEM LGLGVGILAG
300
301
CLCLLLAVYF IAQKIRKKRL GNRKSVVFTS ARATTEA              
337
 

Show the unformatted sequence.

Checksums:
CRC64:32F02F4DB78AC0C9
MD5:5254515639ae353ce980ffae23f46683

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Carb_anhydrase 22 - 278 1RJ5 A 5 - 260 Jmol AstexViewer SPICE
B 5 - 260 Jmol AstexViewer SPICE
1RJ6 A 5 - 260 Jmol AstexViewer SPICE
B 5 - 260 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.