Summary
This is the summary of UniProt entry CAH14_MOUSE (Q9WVT6).
| Description: | Carbonic anhydrase 14 EC=4.2.1.1 |
| Source organism: |
Mus musculus (Mouse)
(NCBI taxonomy ID
10090)
View Pfam proteome data. |
| Length: | 337 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 15 |
| Pfam A | Carb_anhydrase | 22 | 278 |
| disorder | n/a | 24 | 28 |
| disorder | n/a | 30 | 44 |
| disorder | n/a | 67 | 77 |
| disorder | n/a | 80 | 84 |
| disorder | n/a | 119 | 127 |
| disorder | n/a | 245 | 253 |
| disorder | n/a | 255 | 257 |
| disorder | n/a | 259 | 262 |
| transmembrane | n/a | 290 | 312 |
| low_complexity | n/a | 291 | 308 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q9WVT6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MLFFALLLKV TWILAADGGH HWTYEGPHGQ DHWPTSYPEC GGDAQSPINI
50 51
QTDSVIFDPD LPAVQPHGYD QLGTEPLDLH NNGHTVQLSL PPTLHLGGLP
100 101
RKYTAAQLHL HWGQRGSLEG SEHQINSEAT AAELHVVHYD SQSYSSLSEA
150 151
AQKPQGLAVL GILIEVGETE NPAYDHILSR LHEIRYKDQK TSVPPFSVRE
200 201
LFPQQLEQFF RYNGSLTTPP CYQSVLWTVF NRRAQISMGQ LEKLQETLSS
250 251
TEEDPSEPLV QNYRVPQPLN QRTIFASFIQ AGPLYTTGEM LGLGVGILAG
300 301
CLCLLLAVYF IAQKIRKKRL GNRKSVVFTS ARATTEA
337
Show the unformatted sequence. |
| Checksums: |
CRC64:32F02F4DB78AC0C9
MD5:5254515639ae353ce980ffae23f46683
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| Carb_anhydrase | 22 - 278 | 1RJ5 | A | 5 - 260 | Jmol AstexViewer SPICE |
| B | 5 - 260 | Jmol AstexViewer SPICE | |||
| 1RJ6 | A | 5 - 260 | Jmol AstexViewer SPICE | ||
| B | 5 - 260 | Jmol AstexViewer SPICE |
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.