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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q9WX78_THETH (Q9WX78)

Summary

This is the summary of UniProt entry Q9WX78_THETH (Q9WX78).

Description: RNA polymerase sigma factor
Source organism: Thermus thermophilus (NCBI taxonomy ID 274)
Length: 423 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 79
coiled_coil n/a 6 26
low_complexity n/a 23 71
Pfam A Sigma70_r1_2 78 114
low_complexity n/a 93 108
Pfam A Sigma70_r2 187 257
Pfam A Sigma70_r3 266 345
disorder n/a 286 287
disorder n/a 315 316
disorder n/a 344 346
low_complexity n/a 348 363
Pfam A Sigma70_r4 357 410

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9WX78. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKKSKRKNAQ AQEAQETEVL VQEEAEELPE FPEGEPDPDL EDPDLALEDD
50
51
LLDLPEEGEG LDLEEEEEDL PIPKISTSDP VRQYLHEIGQ VPLLTLEEEV
100
101
ELARKVEEGM EAIKKLSEIT GLDPDLIREV VRAKILGSAR VRHIPGLKET
150
151
LDPKTVEEID QKLKSLPKEH KRYLHIAREG EAARQHLIEA NLRLVVSIAK
200
201
KYTGRGLSFL DLIQEGNQGL IRAVEKFEYK RRFKFSTYAT WWIRQAINRA
250
251
IADQARTIRI PVHMVETINK LSRTARQLQQ ELGREPTYEE IAEAMGPGWD
300
301
AKRVEETLKI AQEPVSLETP IGDEKDSFYG DFIPDEHLPS PVDAATQSLL
350
351
SEELEKALSK LSEREAMVLK LRKGLIDGRE HTLEEVGAFF GVTRERIRQI
400
401
ENKALRKLKY HESRTRKLRD FLD                             
423
 

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Checksums:
CRC64:931A7B40B92CBC05
MD5:16f68e5b36e75beed35e498af5b7524a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Sigma70_r1_2 78 - 114 1IW7 F 78 - 114 Jmol AstexViewer SPICE
P 78 - 114 Jmol AstexViewer SPICE
1SMY F 78 - 114 Jmol AstexViewer SPICE
P 78 - 114 Jmol AstexViewer SPICE
Sigma70_r2 187 - 257 1IW7 F 187 - 257 Jmol AstexViewer SPICE
P 187 - 257 Jmol AstexViewer SPICE
1SMY F 187 - 257 Jmol AstexViewer SPICE
P 187 - 257 Jmol AstexViewer SPICE
Sigma70_r3 266 - 345 1IW7 F 266 - 345 Jmol AstexViewer SPICE
P 266 - 345 Jmol AstexViewer SPICE
1SMY F 266 - 345 Jmol AstexViewer SPICE
P 266 - 345 Jmol AstexViewer SPICE
Sigma70_r4 357 - 410 1IW7 F 357 - 410 Jmol AstexViewer SPICE
P 357 - 410 Jmol AstexViewer SPICE
1SMY F 357 - 410 Jmol AstexViewer SPICE
P 357 - 410 Jmol AstexViewer SPICE