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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: FKBP5_SAIBB (Q9XSH5)

Summary

This is the summary of UniProt entry FKBP5_SAIBB (Q9XSH5).

Description: Peptidyl-prolyl cis-trans isomerase FKBP5 EC=5.2.1.8
Source organism: Saimiri boliviensis boliviensis (Bolivian squirrel monkey) (NCBI taxonomy ID 39432)
Length: 457 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 24
disorder n/a 36 37
Pfam A FKBP_C 43 135
disorder n/a 65 66
disorder n/a 153 156
Pfam A FKBP_C 158 248
disorder n/a 158 164
disorder n/a 202 203
Pfam A TPR_11 316 382
Pfam A TPR_1 318 350
disorder n/a 423 457

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9XSH5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTTDEGAKNS RGNPAATVAE QGEDVTSKKD RGVLKIVKRV GHGEETPMIG
50
51
DRVYVHYNGK LANGKKFDSS HDRNEPFVFS IGKGQVIKAW DIGVATMKKG
100
101
EICHLLCKPE YAYGATGSLP KIPSNATLFF EVELLDFKGE DLLEDGGIIR
150
151
RTKRRGEGYS NPNEGARVQI HLEGRCGGRV FDCRDVAFTV GEGEDHDIPI
200
201
GIDKALEKMQ REEQCILHLG PRYGFGEAGK PKFGIEPNAE LIYEVTLKSF
250
251
EKAKESWEMD TKEKLEQAAI VKEKGTVYFK GGKYVQAVIQ YGKIVSWLEM
300
301
EYGLSEKESK ASESFLLAAF LNLAMCYLKL REYTKAVECC DKALGLDSAN
350
351
EKGLYRRGEA QLLMNEFESA KGDFEKVLEV NPQNKAARLQ IFMCQKKAKE
400
401
HNERDRRTYA NMFKKFAEQD AKEEANKAMS KKTSEGVTNE KLTASHAVEE
450
451
EKPEGHV                                               
457
 

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Checksums:
CRC64:DFF9E1D81F7759A8
MD5:72a9399b95a5779b3c8b082709281f41

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
FKBP_C 158 - 248 1KT1 A 158 - 248 Jmol AstexViewer SPICE
43 - 135 1KT1 A 43 - 135 Jmol AstexViewer SPICE
TPR_1 318 - 350 1KT1 A 318 - 350 Jmol AstexViewer SPICE
TPR_11 316 - 382 1KT1 A 316 - 382 Jmol AstexViewer SPICE