Summary
This is the summary of UniProt entry PTN22_HUMAN (Q9Y2R2).
| Description: | Tyrosine-protein phosphatase non-receptor type 22 EC=3.1.3.48 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 807 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | Y_phosphatase | 54 | 288 |
| disorder | n/a | 305 | 312 |
| disorder | n/a | 322 | 327 |
| disorder | n/a | 330 | 344 |
| disorder | n/a | 453 | 457 |
| disorder | n/a | 465 | 469 |
| Pfam B | Pfam-B_2467 | 466 | 566 |
| disorder | n/a | 510 | 514 |
| disorder | n/a | 547 | 554 |
| low_complexity | n/a | 562 | 576 |
| disorder | n/a | 589 | 590 |
| disorder | n/a | 604 | 616 |
| disorder | n/a | 620 | 622 |
| Pfam B | Pfam-B_7200 | 621 | 769 |
| disorder | n/a | 676 | 705 |
| disorder | n/a | 717 | 751 |
| disorder | n/a | 763 | 780 |
| Pfam B | Pfam-B_8360 | 771 | 805 |
| low_complexity | n/a | 777 | 790 |
| disorder | n/a | 788 | 807 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y2R2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MDQREILQKF LDEAQSKKIT KEEFANEFLK LKRQSTKYKA DKTYPTTVAE
50 51
KPKNIKKNRY KDILPYDYSR VELSLITSDE DSSYINANFI KGVYGPKAYI
100 101
ATQGPLSTTL LDFWRMIWEY SVLIIVMACM EYEMGKKKCE RYWAEPGEMQ
150 151
LEFGPFSVSC EAEKRKSDYI IRTLKVKFNS ETRTIYQFHY KNWPDHDVPS
200 201
SIDPILELIW DVRCYQEDDS VPICIHCSAG CGRTGVICAI DYTWMLLKDG
250 251
IIPENFSVFS LIREMRTQRP SLVQTQEQYE LVYNAVLELF KRQMDVIRDK
300 301
HSGTESQAKH CIPEKNHTLQ ADSYSPNLPK STTKAAKMMN QQRTKMEIKE
350 351
SSSFDFRTSE ISAKEELVLH PAKSSTSFDF LELNYSFDKN ADTTMKWQTK
400 401
AFPIVGEPLQ KHQSLDLGSL LFEGCSNSKP VNAAGRYFNS KVPITRTKST
450 451
PFELIQQRET KEVDSKENFS YLESQPHDSC FVEMQAQKVM HVSSAELNYS
500 501
LPYDSKHQIR NASNVKHHDS SALGVYSYIP LVENPYFSSW PPSGTSSKMS
550 551
LDLPEKQDGT VFPSSLLPTS STSLFSYYNS HDSLSLNSPT NISSLLNQES
600 601
AVLATAPRID DEIPPPLPVR TPESFIVVEE AGEFSPNVPK SLSSAVKVKI
650 651
GTSLEWGGTS EPKKFDDSVI LRPSKSVKLR SPKSELHQDR SSPPPPLPER
700 701
TLESFFLADE DCMQAQSIET YSTSYPDTME NSTSSKQTLK TPGKSFTRSK
750 751
SLKILRNMKK SICNSCPPNK PAESVQSNNS SSFLNFGFAN RFSKPKGPRN
800 801
PPPTWNI
807
Show the unformatted sequence. |
| Checksums: |
CRC64:1ABE8AE89C9D9FBF
MD5:017b07db146c674096aeb8c49277f016
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| Y_phosphatase | 54 - 288 | 2P6X | A | 54 - 288 | Jmol AstexViewer SPICE |
| B | 54 - 288 | Jmol AstexViewer SPICE | |||
| 2QCJ | A | 54 - 288 | Jmol AstexViewer SPICE | ||
| B | 54 - 288 | Jmol AstexViewer SPICE | |||
| 2QCT | A | 54 - 288 | Jmol AstexViewer SPICE | ||
| B | 54 - 288 | Jmol AstexViewer SPICE | |||
| 3BRH | A | 54 - 288 | Jmol AstexViewer SPICE | ||
| B | 54 - 288 | Jmol AstexViewer SPICE | |||
| 3H2X | A | 54 - 288 | Jmol AstexViewer SPICE | ||
| 3OLR | A | 54 - 288 | Jmol AstexViewer SPICE | ||
| B | 54 - 288 | Jmol AstexViewer SPICE | |||
| C | 54 - 288 | Jmol AstexViewer SPICE | |||
| D | 54 - 288 | Jmol AstexViewer SPICE | |||
| 3OMH | A | 54 - 288 | Jmol AstexViewer SPICE | ||
| B | 54 - 288 | Jmol AstexViewer SPICE | |||
| C | 54 - 288 | Jmol AstexViewer SPICE | |||
| D | 54 - 288 | Jmol AstexViewer SPICE |