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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NEMO_HUMAN (Q9Y6K9)

Summary

This is the summary of UniProt entry NEMO_HUMAN (Q9Y6K9).

Description: NF-kappa-B essential modulator
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 419 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 17 53
Pfam A NEMO 44 111
coiled_coil n/a 51 75
coiled_coil n/a 97 131
disorder n/a 126 130
coiled_coil n/a 146 201
disorder n/a 171 172
disorder n/a 178 190
disorder n/a 195 197
Pfam B Pfam-B_24245 201 279
disorder n/a 210 218
coiled_coil n/a 213 240
disorder n/a 249 253
coiled_coil n/a 253 294
low_complexity n/a 259 280
disorder n/a 260 263
coiled_coil n/a 312 353
low_complexity n/a 313 339
disorder n/a 323 324
disorder n/a 358 369
low_complexity n/a 364 393
disorder n/a 372 388
disorder n/a 392 398

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y6K9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNRHLWKSQL CEMVQPSGGP AADQDVLGEE SPLGKPAMLH LPSEQGAPET
50
51
LQRCLEENQE LRDAIRQSNQ ILRERCEELL HFQASQREEK EFLMCKFQEA
100
101
RKLVERLGLE KLDLKRQKEQ ALREVEHLKR CQQQMAEDKA SVKAQVTSLL
150
151
GELQESQSRL EAATKECQAL EGRARAASEQ ARQLESEREA LQQQHSVQVD
200
201
QLRMQGQSVE AALRMERQAA SEEKRKLAQL QVAYHQLFQE YDNHIKSSVV
250
251
GSERKRGMQL EDLKQQLQQA EEALVAKQEV IDKLKEEAEQ HKIVMETVPV
300
301
LKAQADIYKA DFQAERQARE KLAEKKELLQ EQLEQLQREY SKLKASCQES
350
351
ARIEDMRKRH VEVSQAPLPP APAYLSSPLA LPSQRRSPPE EPPDFCCPKC
400
401
QYQAPDMDTL QIHVMECIE                                  
419
 

Show the unformatted sequence.

Checksums:
CRC64:322D1037881447FF
MD5:79da7dd0175e2fbba9332d6b6a1367ef

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
NEMO 49 - 109 3BRT B 49 - 109 Jmol AstexViewer SPICE
3BRV B 49 - 109 Jmol AstexViewer SPICE
49 - 110 3BRT D 49 - 110 Jmol AstexViewer SPICE
3BRV D 49 - 110 Jmol AstexViewer SPICE