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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PCLO_HUMAN (Q9Y6V0)

Summary

This is the summary of UniProt entry PCLO_HUMAN (Q9Y6V0).

Description: Protein piccolo
Source organism: Homo sapiens (Human)
Length: 5065 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam B Pfam-B_36002 1 69
disorder n/a 1 164
low_complexity n/a 4 33
low_complexity n/a 157 171
disorder n/a 166 535
low_complexity n/a 186 200
low_complexity n/a 205 226
low_complexity n/a 293 315
low_complexity n/a 344 375
low_complexity n/a 444 471
low_complexity n/a 474 500
Pfam A zf-piccolo 531 592
disorder n/a 592 1013
low_complexity n/a 619 632
low_complexity n/a 816 834
low_complexity n/a 895 909
low_complexity n/a 911 930
low_complexity n/a 941 962
Pfam A zf-piccolo 1001 1054
disorder n/a 1019 1021
disorder n/a 1044 1112
low_complexity n/a 1092 1110
disorder n/a 1114 1596
low_complexity n/a 1149 1166
low_complexity n/a 1169 1190
low_complexity n/a 1247 1258
low_complexity n/a 1269 1289
low_complexity n/a 1327 1338
low_complexity n/a 1385 1405
low_complexity n/a 1443 1453
low_complexity n/a 1493 1507
low_complexity n/a 1514 1538
Pfam B Pfam-B_61730 1551 1582
disorder n/a 1598 1803
low_complexity n/a 1664 1677
low_complexity n/a 1702 1746
coiled_coil n/a 1703 1737
low_complexity n/a 1785 1796
disorder n/a 1825 1849
coiled_coil n/a 1835 1855
disorder n/a 1855 1860
disorder n/a 1864 1865
disorder n/a 1899 1919
disorder n/a 1925 1929
disorder n/a 1976 1980
disorder n/a 1986 1988
disorder n/a 1990 1995
disorder n/a 2000 2035
disorder n/a 2040 2044
low_complexity n/a 2042 2057
disorder n/a 2053 2055
disorder n/a 2058 2060
disorder n/a 2062 2065
disorder n/a 2067 2070
disorder n/a 2072 2076
disorder n/a 2078 2081
disorder n/a 2091 2092
disorder n/a 2098 2122
low_complexity n/a 2105 2130
disorder n/a 2133 2136
disorder n/a 2148 2150
disorder n/a 2174 2183
disorder n/a 2187 2192
disorder n/a 2206 2213
disorder n/a 2216 2223
disorder n/a 2227 2232
disorder n/a 2254 2280
disorder n/a 2282 2286
disorder n/a 2289 2469
low_complexity n/a 2305 2318
low_complexity n/a 2336 2361
low_complexity n/a 2364 2375
low_complexity n/a 2414 2426
low_complexity n/a 2434 2451
disorder n/a 2483 2501
low_complexity n/a 2485 2496
disorder n/a 2514 2534
low_complexity n/a 2545 2557
disorder n/a 2612 2613
disorder n/a 2742 2745
disorder n/a 2748 2763
disorder n/a 2768 2774
low_complexity n/a 2800 2811
disorder n/a 2810 2812
disorder n/a 2814 2817
disorder n/a 2821 2823
disorder n/a 2825 2831
disorder n/a 2834 2843
disorder n/a 2846 2849
disorder n/a 2851 2857
Pfam B Pfam-B_3372 2860 2892
disorder n/a 2891 2901
disorder n/a 2916 2921
disorder n/a 2954 2960
disorder n/a 2964 2965
disorder n/a 2967 3002
disorder n/a 3005 3008
disorder n/a 3036 3037
disorder n/a 3057 3064
disorder n/a 3069 3075
disorder n/a 3109 3110
coiled_coil n/a 3137 3160
low_complexity n/a 3137 3161
disorder n/a 3145 3146
low_complexity n/a 3167 3180
coiled_coil n/a 3213 3244
low_complexity n/a 3214 3241
disorder n/a 3249 3268
disorder n/a 3292 3293
disorder n/a 3327 3329
disorder n/a 3332 3470
disorder n/a 3476 3478
disorder n/a 3483 3484
disorder n/a 3489 3559
disorder n/a 3566 3691
disorder n/a 3694 3699
coiled_coil n/a 3694 3731
Pfam B Pfam-B_4130 3700 3767
disorder n/a 3704 3731
low_complexity n/a 3738 3753
disorder n/a 3739 3852
disorder n/a 3857 3859
disorder n/a 3861 3888
low_complexity n/a 3866 3886
low_complexity n/a 3950 3964
low_complexity n/a 4007 4018
disorder n/a 4008 4013
disorder n/a 4022 4023
disorder n/a 4037 4042
disorder n/a 4050 4051
disorder n/a 4127 4131
disorder n/a 4133 4135
disorder n/a 4137 4139
disorder n/a 4145 4146
low_complexity n/a 4147 4163
disorder n/a 4148 4149
low_complexity n/a 4188 4199
disorder n/a 4200 4235
low_complexity n/a 4213 4228
low_complexity n/a 4232 4248
disorder n/a 4241 4243
disorder n/a 4245 4247
disorder n/a 4256 4344
disorder n/a 4362 4364
disorder n/a 4367 4411
disorder n/a 4415 4416
disorder n/a 4457 4460
disorder n/a 4474 4478
disorder n/a 4484 4515
low_complexity n/a 4516 4532
disorder n/a 4531 4568
low_complexity n/a 4540 4562
Pfam A C2 4580 4669
disorder n/a 4617 4624
disorder n/a 4680 4924
low_complexity n/a 4698 4716
low_complexity n/a 4735 4751
coiled_coil n/a 4771 4791
low_complexity n/a 4774 4784
low_complexity n/a 4864 4888
Pfam A C2 4949 5039

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y6V0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGNEASLEGE GLPEGLAAAA AAGGGASGAG SPSHTAIPAG MEADLSQLSE
50
51
EERRQIAAVM SRAQGLPKGS VPPAAAESPS MHRKQELDSS HPPKQSGRPP
100
101
DPGRPAQPGL SKSRTTDTFR SEQKLPGRSP STISLKESKS RTDLKEEHKS
150
151
SMMPGFLSEV NALSAVSSVV NKFNPFDLIS DSEASQEETT KKQKVVQKEQ
200
201
GKPEGIIKPP LQQQPPKPIP KQQGPGRDPL QQDGTPKSIS SQQPEKIKSQ
250
251
PPGTGKPIQG PTQTPQTDHA KLPLQRDASR PQTKQADIVR GESVKPSLPS
300
301
PSKPPIQQPT PGKPPAQQPG HEKSQPGPAK PPAQPSGLTK PLAQQPGTVK
350
351
PPVQPPGTTK PPAQPLGPAK PPAQQTGSEK PSSEQPGPKA LAQPPGVGKT
400
401
PAQQPGPAKP PTQQVGTPKP LAQQPGLQSP AKAPGPTKTP VQAKPPSQQP
450
451
GSTKPPPQQP GPAKPSPQQP GSTKPPSQQP GSAKPSAQQP SPAKPSAQQS
500
501
TKPVSQTGSG KPLQPPTVSP SAKQPPSQGL PKTICPLCNT TELLLHVPEK
550
551
ANFNTCTECQ TTVCSLCGFN PNPHLTEVKE WLCLNCQMKR ALGGDLAPVP
600
601
SSPQPKLKTA PVTTTSAVSK SSPQPQQTSP KKDAAPKQDL SKAPEPKKPP
650
651
PLVKQPTLHG SPSAKAKQPP EADSLSKPAP PKEPSVPSEQ DKAPVADDKP
700
701
KQPKMVKPTT DLVSSSSATT KPDIPSSKVQ SQAEEKTTPP LKTDSAKPSQ
750
751
SFPPTGEKVS PFDSKAIPRP ASDSKIISHP GPSSESKGQK QVDPVQKKEE
800
801
PKKAQTKMSP KPDAKPMPKG SPTPPGPRPT AGQTVPTPQQ SPKPQEQSRR
850
851
FSLNLGSITD APKSQPTTPQ ETVTGKLFGF GASIFSQASN LISTAGQPGP
900
901
HSQSGPGAPM KQAPAPSQPP TSQGPPKSTG QAPPAPAKSI PVKKETKAPA
950
951
AEKLEPKAEQ APTVKRTETE KKPPPIKDSK SLTAEPQKAV LPTKLEKSPK
1000
1001
PESTCPLCKT ELNIGSKDPP NFNTCTECKN QVCNLCGFNP TPHLTENCQT
1050
1051
QRAISGQLGD IRKMPPAPSG PKASPMPVPT ESSSQKTAVP PQVKLVKKQE
1100
1101
QEVKTEAEKV ILEKVKETLS MEKIPPMVTT DQKQEESKLE KDKASALQEK
1150
1151
KPLPEEKKLI PEEEKIRSEE KKPLLEEKKP TPEDKKLLPE AKTSAPEEQK
1200
1201
HDLLKSQVQI AEEKLEGRVA PKTVQEGKQP QTKMEGLPSG TPQSLPKEDD
1250
1251
KTTKTIKEQP QPPCTAKPDQ EKEDDKSDTS SSQQPKSPQG LSDTGYSSDG
1300
1301
ISSSLGEIPS LIPTDEKDIL KGLKKDSFSQ ESSPSSPSDL AKLESTVLSI
1350
1351
LEAQASTLAD EKSEKKTQPH EVSPEQPKDQ EKTQSLSETL EITISEEEIK
1400
1401
ESQEERKDTF KKDSQQDIPS SKDHKEKSEF VDDITTRREP YDSVEESSES
1450
1451
ENSPVPQRKR RTSVGSSSSD EYKQEDSQGS GEEEDFIRKQ IIEMSADEDA
1500
1501
SGSEDDEFIR NQLKEISSST ESQKKEETKG KGKITAGKHR RLTRKSSTSI
1550
1551
DEDAGRRHSW HDEDDEAFDE SPELKYRETK SQESEELVVT GGGGLRRFKT
1600
1601
IELNSTIADK YSAESSQKKT SLYFDEEPEL EMESLTDSPE DRSRGEGSSS
1650
1651
LHASSFTPGT SPTSVSSLDE DSDSSPSHKK GESKQQRKAR HRPHGPLLPT
1700
1701
IEDSSEEEEL REEEELLKEQ EKQREIEQQQ RKSSSKKSKK DKDELRAQRR
1750
1751
RERPKTPPSN LSPIEDASPT EELRQAAEME ELHRSSCSEY SPSIESDPEG
1800
1801
FEISPEKIIE VQKVYKLPTA VSLYSPTDEQ SIMQKEGSQK ALKSAEEMYE
1850
1851
EMMHKTHKYK AFPAANERDE VFEKEPLYGG MLIEDYIYES LVEDTYNGSV
1900
1901
DGSLLTRQEE ENGFMQQKGR EQKIRLSEQI YEDPMQKITD LQKEFYELES
1950
1951
LHSVVPQEDI VSSSFIIPES HEIVDLGTMV TSTEEERKLL DADAAYEELM
2000
2001
KRQQMQLTPG SSPTQAPIGE DMTESTMDFD RMPDASLTSS VLSGASLTDS
2050
2051
TSSATLSIPD VKITQHFSTE EIEDEYVTDY TREIQEIIAH ESLILTYSEP
2100
2101
SESATSVPPS DTPSLTSSVS SVCTTDSSSP ITTLDSITTV YTEPVDMITK
2150
2151
FEDSEEISSS TYFPGSIIDY PEEISVSLDR TAPPDGRASA DHIVISLSDM
2200
2201
ASSIIESVVP KPEGPVADTV STDLLISEKD PVKKAKKETG NGIILEVLEA
2250
2251
YRDKKELEAE RTKSSLSETV FDHPPSSVIA LPMKEQLSTT YFTSGETFGQ
2300
2301
EKPASQLPSG SPSVSSLPAK PRPFFRSSSL DISAQPPPPP PPPPPPPPPP
2350
2351
PPPPPPPLPP PTSPKPTILP KKKLTVASPV TTATPLFDAV TTLETTAVLR
2400
2401
SNGLPVTRIC TTAPPPVPPK PSSIPSGLVF THRPEPSKPP IAPKPVIPQL
2450
2451
PTTTQKPTDI HPKPTGLSLT SSMTLNLVTS ADYKLPSPTS PLSPHSNKSS
2500
2501
PRFSKSLTET YVVITLPSEP GTPTDSSASQ AITSWPLGSP SKDLVSVEPV
2550
2551
FSVVPPVTAV EIPISSEQTF YISGALQTFS ATPVTAPSSF QAAPTSVTQF
2600
2601
LTTEVSKTEV SATRSTAPSV GLSSISITIP PEPLALDNIH LEKPQYKEDG
2650
2651
KLQLVGDVID LRTVPKVEVK TTDKCIDLSA STMDVKRQIT ANEVYGKQIS
2700
2701
AVQPSIINLS VTSSIVTPVS LATETVTFVT CTASASYTTG TESLVGAEHA
2750
2751
MTTPLQLTTS KHAEPPYRIP SDQVFPIARE EAPINLSLGT PAHAVTLAIT
2800
2801
KPVTVPPVGV TNGWTDSTVS QGITDGEVVD LSTTKSHRTV VTMDESTSSV
2850
2851
MTKIIEDEKP VDLTAGRRAV CCDVVYKLPF GRSCTAQQPA TTLPEDRFGY
2900
2901
RDDHYQYDRS GPYGYRGIGG MKPSMSDTNL AEAGHFFYKS KNAFDYSEGT
2950
2951
DTAVDLTSGR VTTGEVMDYS SKTTGPYPET RQVISGAGIS TPQYSTARMT
3000
3001
PPPGPQYCVG SVLRSSNGVV YSSVATPTPS TFAITTQPGS IFSTTVRDLS
3050
3051
GIHTADAVTS LPAMHHSQPM PRSYFITTGA SETDIAVTGI DISASLQTIT
3100
3101
MESLTAETID SVPTLTTASE VFPEVVGDES ALLIVPEEDK QQQQLDLERE
3150
3151
LLELEKIKQQ RFAEELEWER QEIQRFREQE KIMVQKKLEE LQSMKQHLLF
3200
3201
QQEEERQAQF MMRQETLAQQ QLQLEQIQQL QQQLHQQLEE QKIRQIYQYN
3250
3251
YDPSGTASPQ TTTEQAILEG QYAALEGSQF WATEDATTTA SAVVAIEIPQ
3300
3301
SQGWYTVQSD GVTQYIAPPG ILSTVSEIPL TDVVVKEEKQ PKKRSSGAKV
3350
3351
RGQYDDMGEN MTDDPRSFKK IVDSGVQTDD EDATDRSYVS RRRRTKKSVD
3400
3401
TSVQTDDEDQ DEWDMPTRSR RKARVGKYGD SMTEADKTKP LSKVSSIAVQ
3450
3451
TVAEISVQTE PVGTIRTPSI RARVDAKVEI IKHISAPEKT YKGGSLGCQT
3500
3501
EADSDTQSPQ YLSATSPPKD KKRPTPLEIG YSSHLRADST VQLAPSPPKS
3550
3551
PKVLYSPISP LSPGKALESA FVPYEKPLPD DISPQKVLHP DMAKVPPASP
3600
3601
KTAKMMQRSM SDPKPLSPTA DESSRAPFQY TEGYTTKGSQ TMTSSGAQKK
3650
3651
VKRTLPNPPP EEISTGTQST FSTMGTVSRR RICRTNTMAR AKILQDIDRE
3700
3701
LDLVERESAK LRKKQAELDE EEKEIDAKLR YLEMGINRRK EALLKEREKR
3750
3751
ERAYLQGVAE DRDYMSDSEV SSTRPTRIES QHGIERPRTA PQTEFSQFIP
3800
3801
PQTQTESQLV PPTSPYTQYQ YSSPALPTQA PTSYTQQSHF EQQTLYHQQV
3850
3851
SPYQTQPTFQ AVATMSFTPQ VQPTPTPQPS YQLPSQMMVI QQKPRQTTLY
3900
3901
LEPKITSNYE VIRNQPLMIA PVSTDNTFAV SHLGSKYNSL DLRIGLEERS
3950
3951
SMASSPISSI SADSFYADID HHTPRNYVLI DDIGEITKGT AALSTAFSLH
4000
4001
EKDLSKTDRL LRTTETRRSQ EVTDFLAPLQ SSSRLHSYVK AEEDPMEDPY
4050
4051
ELKLLKHQIK QEFRRGTESL DHLAGLSHYY HADTSYRHFP KSEKYSISRL
4100
4101
TLEKQAAKQL PAAILYQKQS KHKKSLIDPK MSKFSPIQES RDLEPDYSSY
4150
4151
MTSSTSSIGG ISSRARLLQD DITFGLRKNI TDQQKFMGSS LGTGLGTLGN
4200
4201
TIRSALQDEA DKPYSSGSRS RPSSRPSSVY GLDLSIKRDS SSSSLRLKAQ
4250
4251
EAEALDVSFS HASSSARTKP TSLPISQSRG RIPIVAQNSE EESPLSPVGQ
4300
4301
PMGMARAAAG PLPPISADTR DQFGSSHSLP EVQQHMREES RTRGYDRDIA
4350
4351
FIMDDFQHAM SDSEAYHLRR EETDWFDKPR ESRLENGHGL DRKLPERLVH
4400
4401
SRPLSQHQEQ IIQMNGKTMH YIFPHARIKI TRDSKDHTVS MQVLEWNGIP
4450
4451
LTSKTYEEVQ SIISQQSGEA EICVRLDLNM LSDSENSQHL ELHEPPKAVD
4500
4501
KAKSPGVDPK QLAAELQKVS LQQSPLVLSS VVEKGSHVHS GPTSAGSSSV
4550
4551
PSPGQPGSPS VSKKKHGSSK LQINYDLGNL IIHILQARNL VPRDNNGYSD
4600
4601
PFVKVYLLPG RGAEYKRRTK HVQKSLNPEW NQTVIYKSIS MEQLKKKTLE
4650
4651
VTVWDYDRFS SNDFLGEVLI DLSSTSHLDN TPRWYPLKEQ TESIDHGKSH
4700
4701
SSQSSQQSPK PSVIKSRSHG IFPDPSKDMQ VPTIEKSHSS PGSSKSSSEG
4750
4751
HLRSHGPSRS QSKTSVTQTH LEDAGAAIAA AEAAVQQLRI QPTAHKSGQS
4800
4801
NHARKQHRHS IAGVLPIQRT QSDNLPPPAN GNQDQSQLAL RKVMSDGPVK
4850
4851
PEGAKPPNHR PAESSVSTGS SGSSFGSGYS VDSEGSSSTA GETNLFPIPR
4900
4901
IGKMGQNGQE PVKQPGVGVG LADTEAKTQV MGEIKIALKK EMKTDGEQLI
4950
4951
VEILQCRNIT YKFKSPDHLP DLYVKIYVMN ISTQKKVIKK KTRVCRHDRE
5000
5001
PSFNETFRFS LSPAGHSLQI LLFSNGGKFM KKTLIGEACI WLDKVDLRKR
5050
5051
IVNWHKLLVS PTQTH                                      
5065
 

Show the unformatted sequence.

Checksums:
CRC64:0CE4F2990F74AFFF
MD5:b2695fc7062cac59157168d2a12dafa1