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1  structure 1  species 0  interactions 4  sequences 1  architecture

Structure: 3NCZ

Summary

3ncz
PDB entry 3ncz: X-Ray Co-structure of Rho-Associated Protein Kinase (ROCK1) with a potent 2H-isoquinolin-1-one inhibitor
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PDB entry 3ncz

X-ray co-structure of rho-associated protein kinase (rock1) with a potent 2h-isoquinolin-1-one inhibitor

Experiment type: Other, resolution 3.00Å
Release date: 2010-12-08
Authors: Li, X.
Species: Homo sapiens (Human

PDBprint

Below is the PDBprint for entry 3ncz.

External database links

Literature

BioLit references

Checking for BioLit entries for 3ncz

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
A 358 402 ROCK1_HUMAN 358 402 Pkinase_C (PF00433)
A 76 338 ROCK1_HUMAN 76 338 Pkinase (PF00069)
B 358 402 ROCK1_HUMAN 358 402 Pkinase_C (PF00433)
B 76 338 ROCK1_HUMAN 76 338 Pkinase (PF00069)
C 358 402 ROCK1_HUMAN 358 402 Pkinase_C (PF00433)
C 76 338 ROCK1_HUMAN 76 338 Pkinase (PF00069)
D 358 402 ROCK1_HUMAN 358 402 Pkinase_C (PF00433)
D 76 338 ROCK1_HUMAN 76 338 Pkinase (PF00069)

Note: This mapping was provided by the PDBe group.

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