Summary
PDB entry 3qx3
Human topoisomerase iibeta in complex with dna and etoposide
| Experiment type: | Other, resolution 2.16Å |
| Release date: | 2011-07-06 |
| Authors: | Wu, C.C., Li, T.K., Farh, L., Lin, L.Y., Lin, T.S., Yu, Y.J., Yen, T.J., Chiang, C.W., Chan, N.L. |
| Species: | Homo sapiens (Human |
PDBprint
Below is the PDBprint for entry 3qx3.
External database links
| PDBe | 3qx3 |
| RCSB PDB | 3qx3 |
| PDBsum | 3qx3 |
| CATH | 3qx3 |
| SCOP | 3qx3 |
| Proteopedia | 3qx3 |
Literature
BioLit references
Domain organisation
Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.
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Sequence mapping
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.
| PDB | UniProt | Pfam family | ||||
|---|---|---|---|---|---|---|
| Chain | Start | End | ID | Start | End | |
| A | 729 | 1185 | TOP2B_HUMAN | 734 | 1190 | DNA_topoisoIV (PF00521) |
| A | 472 | 588 | TOP2B_HUMAN | 477 | 593 | Toprim (PF01751) |
| B | 729 | 1185 | TOP2B_HUMAN | 734 | 1190 | DNA_topoisoIV (PF00521) |
| B | 472 | 588 | TOP2B_HUMAN | 477 | 593 | Toprim (PF01751) |
Note: This mapping was provided by the PDBe group.
View structure
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